Restrictive Fluids in ERAS Harmful?

RELIEF Trial finds an increased risk of acute kidney injury in the most restrictive fluid protocols in abdominal surgery. They advocate “modestly liberal” fluid regimes. This is a surprise and counter to current regimes of Enhanced Recovery after Surgery (ERAS)

The issue is more nuanced depending on oral intake and how oliguria and hemodynamic perturbation is managed but the overall message seems to be that  ultra restrictive regimes need not necessarily dictate practice at the expense of the kidneys


nejm editorial



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