Whole Blood Resuscitation

Increasing interest is being reported in returning to whole blood rather than component transfusion in trauma. Much of the earlier experience comes from military studies, many of which are subject to selection or survivial biases and retrospective in nature. The overall evidence and rationale, as well as risk, is summarized in this review, with the usual scenario being a combination of whole blood with combination products. Further study is required to define what place whole blood transfusion may have in resuscitation.

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