Dexamethasone use as an anti-emetic has become near universal in anesthesia practice. This systematic review sought to ascertain whether it causes adverse side-effects.
The primary outcomes were postoperative systemic or wound infection, delayed wound healing and glycemic response within 24 h.
No link to wound infections was found, while it was unclear whether it affected wound healing. Mild increases in glucose within 12 hours occurred (mean difference 0.7mmol/L).