Phenylephrine vs. Norepinephrine in Cesarean

A growing interest in the use of small bolus Norepinephrine (Noradrenaline) for Cesarean hypotension is based on its presumed lesser tendency to cause bradycardia compared to Phenylephrine.

This small study compared the effects of 100 μg phenylephrine and 5 μg norepinephrine and found no difference in maternal bradycardia. The number of boluses needed was higher in the Phenylephrine group.

“However, in view of the lower umbilical artery pH when using noradrenaline, further research is warranted to study its placental transfer and fetal metabolic effects”.

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