An observational study to identify the prevalence and predictors of adverse events during sedation for paediatric endoscopy. The incidences of adverse events and adverse respiratory events were 3.4 and 3.3%, respectively.
12 independent predictors: age, children’s size for example underweight/overweight, morbid obesity, presence of respiratory comorbidities, recent respiratory infection, neurological comorbidities, upper gastrointestinal endoscopy, propofol co-administration with ketamine or after sevoflurane induction, and propofol induction dose.
Posthoc secondary analyses revealed a significantly higher risk of adverse events and also significantly more respiratory comorbidities and respiratory infections in children aged less than 2 years when compared with children aged at least 2 years. No cardiovascular events were observed.
Adverse events were rare but predictable and pediatric endoscopy is safe in experienced hands.