Dexmedetomidine + Propofol for Colonoscopy?

Numerous adjuvants to Propofol have been used for colonoscopy sedation, such as Midazolam or more recently Ketamine or Lidocaine. This study supports Propofol as a sole agent.

Combining a low dose of dexmedetomidine with propofol decreased propofol consumption in adults having ambulatory colonoscopy, with no increase in sustained bradycardia. However, using only propofol for colonoscopy provided more stable hemodynamics, faster recovery from anesthesia, and faster attainment of discharge readiness, compared with using propofol–dexmedetomidine.

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